| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| CA-01 | Doug LamalfaREP | REP | 314,036 | 59.0% | R+18.1 |
| CA-02 | DEM | 330,766 | 76.8% | D+53.7 | |
| CA-03 | DEM | 256,966 | 59.4% | D+18.7 | |
| CA-04 | REP | 350,978 | 62.7% | R+25.4 | |
| CA-05 | DEM | 292,091 | 76.9% | D+53.7 | |
| CA-06 | DEM | 235,413 | 75.4% | D+50.9 | |
| CA-07 | Ami BeraDEM | DEM | 297,301 | 51.2% | D+2.3 |
| CA-08 | Paul CookREP | REP | 220,007 | 62.3% | R+24.5 |
| CA-09 | DEM | 232,155 | 57.4% | D+14.7 | |
| CA-10 | Jeff DenhamREP | REP | 241,141 | 51.7% | R+3.4 |
| CA-11 | DEM | 298,209 | 72.0% | D+44.1 | |
| CA-12 | Nancy PelosiDEM | DEM | 338,845 | 80.9% | D+80.9 |
| CA-13 | Barbara LeeDEM | DEM | 322,871 | 90.8% | D+81.6 |
| CA-14 | DEM | 286,447 | 80.9% | D+61.7 | |
| CA-15 | DEM | 269,197 | 73.8% | D+47.5 | |
| CA-16 | Jim CostaDEM | DEM | 167,956 | 58.0% | D+16.1 |
| CA-17 | Ro KhannaDEM | DEM | 233,192 | 61.0% | D+100.0 |
| CA-18 | Anna G EshooDEM | DEM | 323,930 | 71.2% | D+42.3 |
| CA-19 | Zoe LofgrenDEM | DEM | 245,863 | 73.9% | D+47.9 |
| CA-20 | DEM | 255,791 | 70.8% | D+41.5 | |
| CA-21 | REP | 132,408 | 56.7% | R+13.5 | |
| CA-22 | REP | 234,966 | 67.6% | R+35.1 | |
| CA-23 | REP | 241,584 | 69.2% | R+38.4 | |
| CA-24 | DEM | 310,814 | 53.4% | D+6.8 | |
| CA-25 | REP | 261,161 | 53.1% | R+6.3 | |
| CA-26 | DEM | 280,307 | 60.4% | D+20.8 | |
| CA-27 | Judy ChuDEM | DEM | 250,632 | 67.4% | D+34.8 |
| CA-28 | DEM | 270,409 | 78.0% | D+56.0 | |
| CA-29 | DEM | 171,824 | 74.7% | D+100.0 | |
| CA-30 | Brad ShermanDEM | DEM | 282,604 | 72.6% | D+45.3 |
| CA-31 | Pete AguilarDEM | DEM | 215,936 | 56.1% | D+12.1 |
| CA-32 | DEM | 186,646 | 61.6% | D+100.0 | |
| CA-33 | Ted W LieuDEM | DEM | 330,219 | 66.4% | D+32.9 |
| CA-34 | DEM | 159,156 | 77.2% | D+100.0 | |
| CA-35 | DEM | 171,353 | 72.4% | D+44.8 | |
| CA-36 | Raul RuizDEM | DEM | 232,617 | 62.0% | D+24.1 |
| CA-37 | Karen BassDEM | DEM | 237,272 | 81.1% | D+100.0 |
| CA-38 | DEM | 232,114 | 70.5% | D+41.0 | |
| CA-39 | REP | 263,456 | 57.2% | R+14.5 | |
| CA-40 | DEM | 149,297 | 71.4% | D+71.4 | |
| CA-41 | DEM | 197,323 | 65.0% | D+29.9 | |
| CA-42 | Ken CalvertREP | REP | 254,236 | 58.8% | R+17.6 |
| CA-43 | DEM | 219,516 | 76.1% | D+52.2 | |
| CA-44 | DEM | 178,413 | 52.2% | D+100.0 | |
| CA-45 | Mimi WaltersREP | REP | 311,849 | 58.6% | R+17.1 |
| CA-46 | Lou CorreaDEM | DEM | 164,593 | 70.0% | D+100.0 |
| CA-47 | DEM | 242,868 | 63.7% | D+27.4 | |
| CA-48 | REP | 306,416 | 58.3% | R+16.6 | |
| CA-49 | REP | 310,155 | 50.3% | R+0.5 | |
| CA-50 | REP | 283,583 | 63.5% | R+26.9 | |
| CA-51 | Juan VargasDEM | DEM | 199,524 | 72.8% | D+45.5 |
| CA-52 | DEM | 320,656 | 56.5% | D+13.1 | |
| CA-53 | DEM | 296,956 | 67.0% | D+34.0 |