| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| MO-01 | Wm Lacy ClayDEM | DEM | 340,583 | 78.7% | D+60.8 |
| MO-02 | Ann WagnerREP | REP | 394,448 | 60.1% | R+23.0 |
| MO-03 | REP | 338,385 | 63.5% | R+30.6 | |
| MO-04 | REP | 318,723 | 60.3% | R+24.8 | |
| MO-05 | DEM | 330,942 | 60.5% | D+23.6 | |
| MO-06 | Sam GravesREP | REP | 333,688 | 65.0% | R+32.5 |
| MO-07 | Billy LongREP | REP | 318,740 | 63.9% | R+33.0 |
| MO-08 | REP | 300,391 | 71.9% | R+47.4 |