| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| SC-01 | Tim ScottREP | REP | 290,013 | 62.0% | R+28.2 |
| SC-02 | Joe WilsonREP | REP | 203,718 | 96.3% | R+96.3 |
| SC-03 | Jeff DuncanREP | REP | 254,763 | 66.5% | R+33.3 |
| SC-04 | Trey GowdyREP | REP | 266,884 | 64.9% | R+33.4 |
| SC-05 | REP | 278,003 | 55.5% | R+14.5 | |
| SC-06 | DEM | 233,615 | 93.6% | D+93.6 | |
| SC-07 | REP | 275,738 | 55.5% | R+13.9 |