| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| MO-01 | Cori BushDEM | DEM | 316,171 | 78.8% | D+59.8 |
| MO-02 | Ann WagnerREP | REP | 449,348 | 51.9% | R+6.4 |
| MO-03 | REP | 407,348 | 69.4% | R+40.9 | |
| MO-04 | REP | 362,836 | 67.6% | R+37.9 | |
| MO-05 | DEM | 352,430 | 58.8% | D+20.2 | |
| MO-06 | Sam GravesREP | REP | 385,779 | 67.1% | R+36.2 |
| MO-07 | Billy LongREP | REP | 369,283 | 68.9% | R+42.3 |
| MO-08 | REP | 330,226 | 76.9% | R+55.5 |