| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| PA-01 | DEM | 122,264 | 81.5% | D+63.0 | |
| PA-02 | Chaka FattahDEM | DEM | 140,377 | 85.9% | D+71.8 |
| PA-03 | DEM | 147,911 | 62.7% | D+25.4 | |
| PA-04 | Ron KlinkDEM | DEM | 185,630 | 64.2% | D+28.3 |
| PA-05 | REP | 145,431 | 99.9% | R+99.9 | |
| PA-06 | Tim HoldenDEM | DEM | 158,633 | 56.8% | D+13.5 |
| PA-07 | Curt WeldonREP | REP | 197,325 | 69.7% | R+39.3 |
| PA-08 | REP | 167,174 | 66.1% | R+39.4 | |
| PA-09 | Bud ShusterREP | REP | 147,203 | 99.7% | R+99.7 |
| PA-10 | REP | 162,890 | 65.7% | R+34.6 | |
| PA-11 | DEM | 153,277 | 66.5% | D+33.1 | |
| PA-12 | DEM | 171,005 | 68.9% | D+37.8 | |
| PA-13 | Jon D FoxREP | REP | 194,788 | 49.4% | R+4.2 |
| PA-14 | DEM | 164,210 | 64.1% | D+31.7 | |
| PA-15 | Paul McHaleDEM | DEM | 150,909 | 47.8% | D+0.3 |
| PA-16 | REP | 157,455 | 69.7% | R+39.4 | |
| PA-17 | REP | 133,975 | 99.9% | R+99.9 | |
| PA-18 | DEM | 185,750 | 54.8% | D+9.6 | |
| PA-19 | REP | 125,117 | 99.5% | R+99.5 | |
| PA-20 | DEM | 179,419 | 53.1% | D+6.2 | |
| PA-21 | Phil EnglishREP | REP | 180,829 | 49.5% | R+2.6 |