| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| PA-01 | DEM | 165,945 | 87.5% | D+75.0 | |
| PA-02 | Chaka FattahDEM | DEM | 191,937 | 88.0% | D+76.0 |
| PA-03 | DEM | 175,801 | 68.9% | D+37.8 | |
| PA-04 | Ron KlinkDEM | DEM | 222,167 | 64.2% | D+28.4 |
| PA-05 | REP | 193,003 | 60.3% | R+20.6 | |
| PA-06 | Tim HoldenDEM | DEM | 196,729 | 58.5% | D+17.9 |
| PA-07 | Curt WeldonREP | REP | 246,666 | 66.9% | R+34.5 |
| PA-08 | REP | 226,322 | 59.1% | R+23.8 | |
| PA-09 | Bud ShusterREP | REP | 192,822 | 73.7% | R+47.4 |
| PA-10 | REP | 208,540 | 59.8% | R+23.6 | |
| PA-11 | DEM | 188,609 | 68.0% | D+36.0 | |
| PA-12 | DEM | 195,481 | 70.0% | D+40.0 | |
| PA-13 | Jon D FoxREP | REP | 245,979 | 48.9% | R+0.0 |
| PA-14 | DEM | 202,578 | 60.7% | D+21.7 | |
| PA-15 | Paul McHaleDEM | DEM | 200,363 | 54.8% | D+13.5 |
| PA-16 | REP | 209,602 | 59.4% | R+21.9 | |
| PA-17 | REP | 208,616 | 72.2% | R+44.5 | |
| PA-18 | DEM | 214,990 | 56.0% | D+15.6 | |
| PA-19 | REP | 208,963 | 62.5% | R+26.7 | |
| PA-20 | DEM | 210,402 | 53.9% | D+7.8 | |
| PA-21 | Phil EnglishREP | REP | 210,888 | 50.7% | R+1.4 |